Source:
Generated By: https://synbiohub.org/public/igem/igem2sbol/1
Created by: Changlong Zhao
Date created: 2013-09-15 11:00:00
Date modified: 2015-06-08 02:58:23
promoter sdpR/I
| Types | DnaRegion |
| Roles | promoter Regulatory |
| Sequences | BBa_K1074013_sequence (Version 1) |
Description
This part is a sigma factor A-dependent promotor of the gene sdpR derived from the B.subtilis ,and it contains an operon for the signaling pathway of sdpc,a bacterial toxin of B.subtilis. It's activated as the toxin sdpC existed,while the natural pructrue of the promotor, sdpR/I ,confers immunity to the SdpC toxin. Cells of B. subtilis enter the pathway tosporulate under conditions of nutrient limitation could generate sdpC, then this promotor would be activated. We use this part to overexpress sdpC toxin in spore-forming cells,to build a self-killing system in B.subtilis for safety thinking.