BBa_K415501 1 RUNX2 RUNX2 L1L2 MammoBlock Entry Vector 2010-10-23T11:00:00Z 2015-05-08T01:12:27Z Obtained as an L1L2 Entry vector from Open Biosystems. RUNX2, or runt-related transcription factor, is a master osteoblast differentiation transcription factor; it is a downstream target of BMP-2 and switches on transcription of multiple effectors of osteoblast development. NCBI page with sequence, gene information etc. http://www.ncbi.nlm.nih.gov/gene/860 Isoforms: There are three isoforms of RUNX2 in humans, this part contains isoform Type-II, alpha, which is the longest and includes the 3' exon. false false _525_ 0 6768 9 It's complicated false We wanted to use the longest RUNX2 isoform; this isoform has been shown to induce bone differentiation when transfected into human cells. false Laura Deming, Joy Jiao, Adrian Slusarczyk annotation2113486 1 RUNX2 cDNA range2113486 1 21 1605 BBa_K415501_sequence 1 aagggccgtcaaggcccaccgtacaaaaaagcagaagggccgtcaaggcccaccatgcgtattcccgtagatccgagcaccagccggcgcttcagccccccctccagcagcctgcagcccggcaaaatgagcgacgtgagcccggtggtggctgcgcaacagcagcagcaacagcagcagcagcaacagcagcagcagcagcagcaacagcagcagcagcagcaggaggcggcggcggcggctgcggcggcggcggcggctgcggcggcggcagctgcagtgccccggttgcggccgccccacgacaaccgcaccatggtggagatcatcgccgaccacccggccgaactcgtccgcaccgacagccccaacttcctgtgctcggtgctgccctcgcactggcgctgcaacaagaccctgcccgtggccttcaaggtggtagccctcggagaggtaccagatgggactgtggttactgtcatggcgggtaacgatgaaaattattctgctgagctccggaatgcctctgctgttatgaaaaaccaagtagcaaggttcaacgatctgagatttgtgggccggagtggacgaggcaagagtttcaccttgaccataaccgtcttcacaaatcctccccaagtagctacctatcacagagcaattaaagttacagtagatggacctcgggaacccagaaggcacagacagaagcttgatgactctaaacctagtttgttctctgaccgcctcagtgatttagggcgcattcctcatcccagtatgagagtaggtgtcccgcctcagaacccacggccctccctgaactctgcaccaagtccttttaatccacaaggacagagtcagattacagaccccaggcaggcacagtcttccccgccgtggtcctatgaccagtcttacccctcctacctgagccagatgacgtccccgtccatccactctaccaccccgctgtcttccacacggggcactgggcttcctgccatcaccgatgtgcctaggcgcatttcagatgatgacactgccacctctgacttctgcctctggccttccactctcagtaagaagagccaggcaggtgcttcagaactgggccctttttcagaccccaggcagttcccaagcatttcatccctcactgagagccgcttctccaacccacgaatgcactatccagccacctttacttacaccccgccagtcacctcaggcatgtccctcggtatgtccgccaccactcactaccacacctacctgccaccaccctaccccggctcttcccaaagccagagtggacccttccagaccagcagcactccatatctctactatggcacttcgtcaggatcctatcagtttcccatggtgccggggggagaccggtctccttccagaatgcttccgccatgcaccaccacctcgaatggcagcacgctattaaatccaaatttgcctaaccagaatgatggtgttgacgctgatggaagccacagcagttccccaactgttttgaattctagtggcagaatggatgaatctgtttggcgaccatattagggcctcatgggcccagctttcttgtactaaggcctcatggg igem2sbol 1 iGEM to SBOL conversion Conversion of the iGEM parts registry to SBOL2.1 Chris J. Myers James Alastair McLaughlin 2017-03-06T15:00:00.000Z