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Showing 1 - 50 of 355 result(s)
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Public
iGEM to SBOL conversion
igem2sbol Version 1 (Activity)
Conversion of the iGEM parts registry to SBOL2.1
Public
SyBiOntKB to SBOL conversion
SyBiOntKB2sbol Version 1 (Activity)
Conversion of the Synthetic Biology Ontology knowledge base to SBOL 2.1
Public
SBOLDesigner CAD Tool
SBOLDesigner Version 3.0 (Agent)
SBOLDesigner is a simple, biologist-friendly CAD software tool for creating and manipulating the sequences of genetic constructs using the Synthetic Biology Open Language (SBOL) 2 data model. Throughout the design process, SBOL Visual symbols, a system of schematic glyphs, provide standardized visualizations of individual parts. SBOLDesigner completes a workflow for users of genetic design automation tools. It combines a simple user interface with the power of the SBOL standard and serves as a launchpad for more detailed designs involving simulations and experiments. Some new features in SBOLDesigner are SynBioHub integration, local repositories, importing of parts/sequences from existing files, import and export of GenBank and FASTA files, extended role ontology support, the ability to partially open designs with multiple root ComponentDefinitions, backward compatibility with SBOL 1.1, and versioning.
Public
SBOLDesigner CAD Tool
SBOLDesigner Version 3.1 (Agent)
SBOLDesigner is a simple, biologist-friendly CAD software tool for creating and manipulating the sequences of genetic constructs using the Synthetic Biology Open Language (SBOL) 2 data model. Throughout the design process, SBOL Visual symbols, a system of schematic glyphs, provide standardized visualizations of individual parts. SBOLDesigner completes a workflow for users of genetic design automation tools. It combines a simple user interface with the power of the SBOL standard and serves as a launchpad for more detailed designs involving simulations and experiments. Some new features in SBOLDesigner are the ability to add variant collections to combinatorial derivations, enumerating those collections, and the ability to view sequence features hierarchically. There are also some small changes to the way that preferences work in regards to saving a design with incomplete sequences.
Public
IBMc475_seq
IBMc475_seq Version 1 (Sequence)

Public
IBMc474_seq
IBMc474_seq Version 1 (Sequence)

Public
IBMc175_seq
IBMc175_seq Version 1 (Sequence)

Public
IBMc415_seq
IBMc415_seq Version 1 (Sequence)

Public
IBMc476_seq
IBMc476_seq Version 1 (Sequence)

Public
IBMc425_seq
IBMc425_seq Version 1 (Sequence)

Public
IBMc477_seq
IBMc477_seq Version 1 (Sequence)

Public
Intein_assisted_Bisection_Mapping
Intein_assisted_Bisection_Mapping_collection Version 1 (Collection)
Split inteins are powerful tools for seamless ligation of synthetic split proteins. Yet, their use remains limited because the already intricate split site identification problem is often complicated by the requirement of extein junction sequences. To address this, we augmented a mini-Mu transposon-based screening approach and devised the intein-assisted bisection mapping (IBM) method. IBM robustly revealed clusters of split sites on five proteins, converting them into AND or NAND logic gates. We further showed that the use of inteins expands functional sequence space for splitting a protein. We also demonstrated the utility of our approach over rational inference of split sites from secondary structure alignment of homologous proteins. Furthermore, the intein inserted at an identified site could be engineered by the transposon again to become partially chemically inducible, and to some extent enabled post-translational tuning on host protein function. Our work offers a generalizable and systematic route towards creating split protein-intein fusions and conditional inteins for protein activity control.
Public
IBMc457_seq
IBMc457_seq Version 1 (Sequence)

Public
IBMc473_seq
IBMc473_seq Version 1 (Sequence)

Public
IBMc471_seq
IBMc471_seq Version 1 (Sequence)

Public
IBMc472_seq
IBMc472_seq Version 1 (Sequence)

Public
IBMc455_seq
IBMc455_seq Version 1 (Sequence)

Public
IBMc405_seq
IBMc405_seq Version 1 (Sequence)

Public
IBMc479_seq
IBMc479_seq Version 1 (Sequence)

Public
IBMc470_seq
IBMc470_seq Version 1 (Sequence)

Public
IBMc478_seq
IBMc478_seq Version 1 (Sequence)

Public
IBMc325_seq
IBMc325_seq Version 1 (Sequence)

Public
IBMc335_seq
IBMc335_seq Version 1 (Sequence)

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IBMc176_seq
IBMc176_seq Version 1 (Sequence)

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IBMc374_seq
IBMc374_seq Version 1 (Sequence)

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IBMc417_seq
IBMc417_seq Version 1 (Sequence)

Public
IBMc427_seq
IBMc427_seq Version 1 (Sequence)

Public
IBMc378_seq
IBMc378_seq Version 1 (Sequence)

Public
IBMc426_seq
IBMc426_seq Version 1 (Sequence)

Public
IBMc428_seq
IBMc428_seq Version 1 (Sequence)

Public
IBMc404_seq
IBMc404_seq Version 1 (Sequence)

Public
IBMc071_seq
IBMc071_seq Version 1 (Sequence)

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IBMc429_seq
IBMc429_seq Version 1 (Sequence)

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IBMc419_seq
IBMc419_seq Version 1 (Sequence)

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IBMc379_seq
IBMc379_seq Version 1 (Sequence)

Public
IBMc078_seq
IBMc078_seq Version 1 (Sequence)

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IBMc372_seq
IBMc372_seq Version 1 (Sequence)

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IBMc403_seq
IBMc403_seq Version 1 (Sequence)

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IBMc370_seq
IBMc370_seq Version 1 (Sequence)

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IBMc400_seq
IBMc400_seq Version 1 (Sequence)

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IBMc414_seq
IBMc414_seq Version 1 (Sequence)

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IBMc416_seq
IBMc416_seq Version 1 (Sequence)

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IBMc371_seq
IBMc371_seq Version 1 (Sequence)

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IBMc065_seq
IBMc065_seq Version 1 (Sequence)

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IBMc402_seq
IBMc402_seq Version 1 (Sequence)

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IBMc401_seq
IBMc401_seq Version 1 (Sequence)

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IBMc421_seq
IBMc421_seq Version 1 (Sequence)

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IBMc373_seq
IBMc373_seq Version 1 (Sequence)

Public
IBMc411_seq
IBMc411_seq Version 1 (Sequence)

Public
IBMc410_seq
IBMc410_seq Version 1 (Sequence)

Showing 1 - 50 of 355 result(s)
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