Source:
Generated By: https://synbiohub.org/public/igem/igem2sbol/1
Created by: Emiel van der Kouwe
Date created: 2013-09-21 11:00:00
Date modified: 2015-08-03 03:10:42
pAceB promoter region
| Types | DnaRegion |
| Roles | promoter Regulatory |
| Sequences | BBa_K1163101_sequence (Version 1) |
Description
Promoter from E. coli that controls the AceB gene, involved in iron uptake and iron sensitive.FUR (Ferric Uptake Regulation) is a transcriptional repressor of genes involved in iron homeostasis. In presence of iron, the FUR protein changes its conformation and dimerizes. This leads to the binding to the DNA on a FUR binding site, thus inhibiting the mRNA transcription.
Why would you use this part?
This promoter allows you to have an iron-sensitive behaviour. In fact, in the presence of iron, the Fes promoter region decreases the expression of the downstream gene.