LL-37

BBa_K1230001 Version 1

Component

Source: http://parts.igem.org/Part:BBa_K1230001

Generated By: https://synbiohub.org/public/igem/igem2sbol/1

Created by: Andr??s Ferri??o Iriarte

Date created: 2013-09-07 11:00:00

Date modified: 2016-02-01 12:49:22

LL-37 antimicrobial peptide

Details

• Types: DnaRegion
• Roles: polypeptide_domain; Protein_Domain
• Sequences: BBa_K1230001_sequence (Version 1)

Description

The human peptide LL-37 is a cationic antimicrobial peptide with activity against Gram-negative and Gram-positive bacteria. It has been shown to protect against Helicobacter pylori infection and its related gastritis, besides of inhibiting the growth of other pathogenic bacteria in the gastrointestinal tract such as Salmonella typhimurium and Escherichia coli.

Notes

Addition of initiation and stop codons.

Source

Synthesis from genscript

Sequence Annotations

Sequence Annotation	Location	Component / Role(s)
LL-37	1,120	feature/cds, CDS
Start	1,3	start_codon, feature/start
Stop	114,120	stop_codon, feature/stop

Other Properties

• igem#experience: None
• igem#sampleStatus: It's complicated
• igem#status: Planning
• synbiohub#ownedBy: user/james
• synbiohub#ownedBy: user/myers
• synbiohub#topLevel: BBa_K1230001/1

Member of these Collections

• //collections/antimicrobial
• iGEM Parts Registry