BBa_K1461107

BBa_K1461107 Version 1

Component

This part has been discontinued.

Source: http://parts.igem.org/Part:BBa_K1461107

Generated By: https://synbiohub.org/public/igem/igem2sbol/1

Created by: Shunsuke Sumi

Date created: 2014-09-22 11:00:00

Date modified: 2015-05-08 01:10:33

EGP-2

Details

• Types: DnaRegion
• Roles: promoter; Regulatory

Description

EGP-2 is located upstream of EPCAM.
this promoter is shortened to sustain promoter function.
this is cloned from human cell.

Notes

EPCAM is expressed in CTC.
Therefore, EGP-2 is considered to be a good candidate for a marker.

Source

1. McLaughlin, P. M., Trzpis, M., Kroesen, B. J., Helfrich, W., Terpstra, P., Dokter, W. H., ... & Harmsen, M. C. (2004). Use of the EGP-2/Ep-CAM promoter for targeted expression of heterologous genes in carcinoma derived cell lines. Cancer gene therapy, 11(9), 603-612.
2.Danda, R., Krishnan, G., Ganapathy, K., Krishnan, U. M., Vikas, K., Elchuri, S., ... & Krishnakumar, S. (2013). Targeted Expression of Suicide Gene by Tissue-Specific Promoter and MicroRNA Regulation for Cancer Gene Therapy. PloS one, 8(12), e83398.

Other Properties

• igem#experience: None
• igem#sampleStatus: Discontinued
• igem#status: Deleted
• synbiohub#ownedBy: user/james
• synbiohub#ownedBy: user/myers
• synbiohub#topLevel: BBa_K1461107/1

Member of these Collections

• iGEM Parts Registry