Source:
Generated By: https://synbiohub.org/public/igem/igem2sbol/1
Created by: Ching-Yuan Chen, Yi-Ru Liu, Pei-Hong Chen
Date created: 2015-09-09 11:00:00
Date modified: 2015-09-13 02:11:11
SR/pSB1C3 (Fire Retardant BioBrick Part)
| Types | DnaRegion |
| Roles | Coding CDS |
| Sequences | BBa_K1608000_sequence (Version 1) |
Description
SR/pSB1C3 is carrying the SR gene encoding Homo sapiens SRSF1 (NCBI GI:5902076). Serine/arginine-rich splicing factor 1 (SRSF1) belonged to SR protein family is involved in pre-mRNA splicing and RNA metabolism. SRSF1 is also known as ASF/SF2 and has a conserved RS domain rich in serine and arginine residues. Its activity is regulated by phosphorylation which is post-translationally modified by SRPK1 kinase. Because phosphoserine and arginine play roles in fire resistance, we used the feature of SR proteins as fire retardant bio-materials.Notes
No EcoRI, XbaI, SpeI, PstI sites on the gene. It is easy to be a standard BioBrick part.Source
The gene source is cloned from cDNA of Homo sapiens.| Sequence Annotation | Location | Component / Role(s) |
| SR protein | 1,747 | sequence_feature feature/misc |