| Types | DnaRegion
|
| Roles | Coding
CDS
|
| Sequences | BBa_K1613004_sequence (Version 1)
|
Description
Cytochrome P450 1A2 is a member of the cytochrome P450 mixed-function oxidase system. And it is involved in the metabolism of xenobiotics in the body.
Notes
The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP1A2 is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include aflatoxin B1, and acetaminophen.
Source
We use humen liver gene cyp1a2(genebank:NM_000761),but we do some chang to remove the restriction site.
