Source:
Generated By: https://synbiohub.org/public/igem/igem2sbol/1
Created by: Marco V. Lincango Y.
Date created: 2016-10-17 11:00:00
Date modified: 2016-10-18 11:34:57
GADL1 Acidic Amino Acid Decarboxylase
| Types | DnaRegion |
| Roles | CDS Coding |
| Sequences | BBa_K2004008_sequence (Version 1) |
Description
GADL1 (Glutamate Decarboxylase Like 1) is a Protein Coding gene. Diseases associated with GADL1 include Gadl1-Related Altered Drug Metabolism. Among its related pathways are Pantothenate and CoA biosynthesis and Taurine and hypotaurine metabolism.GADL1 encodes a member of the group 2 decarboxylase family. A similar protein in rodents plays a role in multiple biological processes as the rate-limiting enzyme in taurine biosynthesis, catalyzing the decarboxylation of cysteine sulfinate to hypotaurine.
The cysteine sulfinic acid decarboxylase enzyme (CSAD), also known as sulfoalanine decarboxylase, is an enzyme involved in the taurine biosynthesis. It is in charge of catalyzing the reaction that decarboxylates cysteine sulfinate generating hypotaurine and CO2. CSAD is a liase, and more specifically a carboxylase (Sumizu, K., 1962)