Source:
Generated By: https://synbiohub.org/public/igem/igem2sbol/1
Created by: Glasgow Uni 2011
Date created: 2011-09-15 11:00:00
Date modified: 2015-05-08 01:13:03
Phosphodiesterase (enzyme)
| Types | DnaRegion |
| Roles | Coding CDS |
| Sequences | BBa_K660300_sequence (Version 1) |
Description
Phosphodiesterases are a family of enzymes naturally present in microorganisms, which break phosphodiester bonds. The specific enzyme we are using breaks the phosphodiester bond in the second messenger nucleotide, cyclic digaunylate (cyclic-di-GMP). Cyclic-di-GMP is important in many bacterial processes, including biofillm formation and motility. The enzyme regulates signal transduction by controlling levels of the signalling molecule in cells.We are using the enzyme to control the levels of cyclic-di-GMP within the cell. We expect that the targeted expression of phosphodesiterase could be used to interfere with biofilm formation or to trigger dispersal.